With over six years of hands-on experience in crafting multifunctional nanomaterials for their applications in biosensing and biomedicine, I bring a wealth of expertise to the table. My skill set encompasses the art of harnessing the optoelectronic and physicochemical properties of transition metal oxides to design and engineer cutting-edge point-of-care biological and chemical sensors.
Presently, I serve as a Post-Doctoral Researcher at the Department of Chemical Engineering within the esteemed National Tsing Hua University. Here, I spearhead pioneering initiatives in the realm of wearable biosensors, geared towards the early detection and continuous monitoring of chronic illnesses. My role involves close collaboration with interdisciplinary teams, bridging the worlds of chemistry, biology, and engineering to conceive and construct monitoring devices that prioritize accuracy, sensitivity, and reliability.
The projects I lead are driven by a resolute commitment to addressing the unmet clinical demands of real-time therapeutic load identification in disease models and ongoing disease progression monitoring. I shoulder the responsibility of meticulous product development oversight, ensuring that our devices align seamlessly with the unique requirements of our stakeholders.
Beyond my professional journey, my academic prowess shines through with a PhD in Analytical Chemistry from National Sun Yat-sen University. I've authored a substantial body of work, publishing numerous papers focused on the development and utilization of nanomaterial-based biosensors in biological fluids. My dual educational background as both a Biotechnologist and Chemist equips me with the ability to devise alternative and patient-centric solutions to intricate biomedical challenges.
Anticipating the road ahead, I am enthusiastic about pivoting towards the Industry, actively seeking dynamic challenges that allow me to channel my research-driven proficiency in Materials and Analytical Chemistry.
Materials Chemistry for Wearable Biosensors
• Accomplished fabrication of dielectric metal oxide nanoparticles that were integrated into Thermoplastic Polyurethane (TPU) polymer-based elastomer for continuous cancer monitoring.
• Fabrication of chemochromic vanadium-based oxide nanomaterial as visual assist for selective biomolecular interaction.
• Fabrication of hydrogel-based wound dressing loaded with electroresponsive nanomaterial for continuous monitoring of wound status through integrated electrodes.
• Execute computational simulation using AutoDock to assess nanomaterial-biomolecule interaction chemistry.
• Supervise and evaluate biochemical and nanomaterial interactions through analytical tools.
Worked under Prof. Rohit Srivastava, NanoBios Lab, Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay
Research Highlights:
• Gained experience on polymeric nanoparticles using PLGA for biomolecule entrapment as a platform for Hepatitis B vaccine delivery.
• Explored various fabrication and analytical approach for biomolecule loaded polymeric nanoparticles and study its release kinetics.
• Gained experience in cellular analysis and bioimaging technique.
Selected through a nationwide competition by the Indian Academy of Sciences for the Summer Research Fellowship Program.
Worked under the guidance of Prof. K.V.A. Ramaiah, Department of Life Science, University of Hyderabad.
Research Highlights:
• Gene expression in a bacterial genome through plasmid incorporation.
• Conduct protein isolation and purification through molecular biology techniques
PAGE, Western blot.
• Study protein activity as molecular chaperones against aggregated protein models.
The Phi Tau Phi Scholastic Honor Society of the Republic of China
Description
Worked under the supervision of Prof. Hui-Fen Wu at the Department of Chemistry, National Sun Yat-sen University.
Research Highlights:
• Explored the fabrication and applicability of oxygen-deficiency in MoO3-x nanosheets as colorimetric biosensors towards physiological biomarkers.
• Fabrication and controlled growth of sub-nanometer fluorescent gold and molybdenum nanoclusters for their applicability in biomarker detection and cancer bioimaging.
• Explored various metal oxide perovskite nanomaterial compositions integrating transition and lanthanide metals for fluorescence-based biomarker detection.
• Gained experience in solid-state and solvent-free nanomaterial synthesis methods aimed at sustainability.
• Experienced in various physicochemical and optoelectronic analytical characterizations of metal oxide and colloidal nanomaterials.
Thesis title: Synthesis and characterization of molybdenum, gold, and perovskite nanomaterials for biomarker analysis