Jason Pruet from OpenAI is a physicist and technology leader with over two decades of experience in science, national security, and public service. He currently serves as a member of the technical staff on the Mission Alignment team, where his work supports the responsible development and use of artificial intelligence for the benefit of humanity. He holds a Ph.D. in Physics from the University of California, San Diego, where his early academic research explored astrophysics and nucleosynthesis. Over his career, he has taken on leadership roles at Lawrence Livermore and Los Alamos National Laboratories. He has spent nearly ten years in federal service guiding intelligence, science, and engineering programs related to nuclear weapons. He earned his doctorate under the supervision of George Fuller, a Nobel laureate and Willy Fowler's student. His dissertation examined the physics behind gamma-ray bursts, focusing on how weak processes influence the engines and fireballs of these powerful cosmic events. This research shaped his early interest in understanding the complex systems driving natural and human-made phenomena. After completing his Ph.D., he joined Lawrence Livermore National Laboratory (LLNL) as a postdoctoral researcher under a SciDAC Supernova grant. He later became the group leader for computational nuclear physics, contributing to national security missions involving stockpile stewardship, technologies for detecting hidden nuclear materials, and methods for forensic attribution. These efforts supported the lab’s core mission to maintain scientific and technical excellence, supporting U.S. security interests. In 2011, he transitioned to public service in Washington, D.C., joining the Department of Energy’s National Nuclear Security Administration (NNSA). He managed nuclear stockpile assessment and modeling programs there, including the Primary Assessment Campaign and Physics and Engineering Models Campaign. He also helped establish a new initiative, Capabilities for Nuclear Intelligence, designed to connect the strengths of the national laboratories with vital intelligence work. By 2013, he was appointed Chief of an intelligence branch within the DOE Office of Intelligence and Counterintelligence, where his team analyzed foreign nuclear weapons programs. His leadership in developing the Foreign Nuclear Weapons Intelligence Initiative earned recognition from the Secretary of Energy and the Office of the Director of National Intelligence. Later, as Director of the Office of Engineering for Stockpile Assessments and Responsiveness at NNSA, he oversaw a $500 million science and engineering portfolio to ensure the reliability and resilience of the U.S. nuclear deterrent. In 2025, he joined OpenAI full-time as part of the Mission Alignment team. There, his focus includes supporting scientific, philanthropic, and national security initiatives while collaborating with researchers, policymakers, and nonprofit organizations to guide AI development in the service of broader societal needs. Throughout his career, Jason Pruet has authored and co-authored numerous peer-reviewed papers and technical reports, including research on nucleosynthesis in gamma-ray burst accretion disks, detection of clandestine materials using gamma rays, and the role of high-performance computing in nuclear security. He also contributed to a roadmap outlining the future of AI for Science, Energy, and Security. His career reflects a lifelong commitment to responsibly applying science and technology to serve humanity and national interests. Learn More: https://scholar.google.com/citations?user=thayWGoAAAAJ&hl