- Managed and mentored a bioinformatics team (3 members), responsible for developing and optimizing production-level NGS data analysis pipelines. - Implemented modular pipeline architectures, ensuring scalability and seamless cross-departmental collaboration with quality assurance, assay design, and operations.

Journal Reviewer | Peer-reviewed articles for leading scientific journals: - Welcome Open Research (2024) - Frontiers in Genetics (2023) - Genes and Genomics (2017) - Evolutionary Bioinformatics (2014–2017) - Cancer Informatics (2014–2017) - Briefings in Bioinformatics (2011–2013) - Special issue of BMC Bioinformatics (ISBRA, 2011)

- Spearheaded innovative bioinformatics research and product development initiatives, bridging R&D activities with clinical assay design and implementation. - Developed prototype pipelines and validated novel concepts to enable seamless transition into regulated clinical environments.

Bioinformatics Division - Pipeline Innovation: Directed the design, development, and maintenance of bioinformatics pipelines in close collaboration with assay development teams, supporting both new product innovations and ongoing workflow enhancements. - Operational Oversight: Managed pipeline operations within a clinical production environment, ensuring reliable performance, rapid troubleshooting, and effective responses to unexpected issues. - Quality & Compliance: Led software quality engineering initiatives, ensuring comprehensive IQ/OQ/PQ validations were performed on all bioinformatics pipelines to meet rigorous regulatory and clinical standards.

- Supervised a team of 8 engineers in NGS pipeline R&D and integration with assay biology. - Acted as liaison between bioinformatics and wet-lab teams to align data workflows with experimental design. - Led algorithm development and Nextflow/Kubernetes-based pipeline deployment. - Completed full refactoring of legacy pipelines into modular Nextflow workflows on Kubernetes.

- Led cross-functional teams in algorithm and pipeline development within a hybrid cloud environment. - Developed NGS workflows emphasizing RNA fusion detection, machine learning-based analytics, and real-time deployment on scalable infrastructure.

- Designed and implemented fusion detection pipelines using Shell, Nextflow, and Kubernetes frameworks. - Contributed to AI/NLP-based algorithm development and integrated CI/CD workflows using Bitbucket and Docker.

- Moved from Academia Sinica to Top Science Biotech, translating academic NGS expertise into product-driven bioinformatics solutions. - Led pipeline development efforts with a focus on clinical utility, scalability, and alignment with commercial goals.

I am now a postdoctoral fellow at Genomics Research Center, Academia Sinica. Currently, I focus on the design of transcriptome analysis pipeline and next-generation sequencing data analysis. Research interests: - DNA/RNA sequencing (DNA-Seq/RNA-Seq/ChIP-Seq/Metegenomics sequencing) - Genome assembly, gene annotation, comparative analysis - genome, mitogenome - Sample type: tissue (normal/tumor), white blood cell, plasma (DNA/RNA/ctDNA) - hands-on experience on sequencing data analysis: SOLiD 5500, Roche 454 GS Junior; Illumina MiSeq, NextSeq 500, HiSeq 2000/4000/XTen; Oxford Nanopore Technology MinION

System administrator of Core Facility, Center for Systems Biology & Bioinformatics,

Teaching course: data structure, information security

Server Maintenance General affairs

Course: computer architecture